The discussion will begin with an overview of viscosity and a description of the microfluidic/MEMS measurement technology with its advantages. The relevance of viscosity to both practical applications and as an investigative tool to gain insight during the formulation process will be explained. Data and analysis will be presented to emphasize the benefits of measuring viscosity in the pharmaceutical and biotech industries. Sample systems will include protein solutions, pharmaceutical excipients, and fully formulated over the counter products. The following testing protocols and analysis techniques will be reviewed.
- Shear rate and temperature sweeps
- Viscosity versus concentration
- Intrinsic viscosity analysis
- Hydrodynamic size estimation
- Injectability analysis